The project develops advanced methodologies and data resources for genome-wide modeling of proteins, protein interactions, and assessment of phenotypic effects of genetic mutations.
Individual chains are either experimental from the Protein Data Bank (PDB) or built by template modeling using Phyre2. Binary complexes are either experimental from the Protein Data Bank or built by template modeling using GRAMM.
|Type of GWYRE Entry||Coordinates of chain 1||Coordinates of chain 2||Structure of GWYRE entry||Number of GWYRE entries|
|PDB + PDB||PDB||PDB||Predicted by GRAMM||859|
|Model + PDB||Model||PDB||Predicted by GRAMM||583|
|Model + Model||Model||Model||Predicted by GRAMM||1,925|
Center for Computational Biology
University of Kansas, Lawrence, KS 66045, USA.
Centre for Integrative Systems Biology and Bioinformatics (CISBIO)
Imperial College London, London. SW7 2AZ, UK.